Effect of N-Acetylcysteine on Air Trapping in COPD – A Randomized Placebo-Controlled Study
Background: FEV1 is used for the classification of disease severity and is a good predictor of COPD mortality. However, it is a poor predictor of clinical symptoms, exercise tolerance, and response to bronchodilators in COPD. Progressive reduction in inspiratory capacity (IC) during exercise reflects dynamic hyperinflation and is a [...]